Dasatinib
Unsuitables - unsuitable to be used as a chemical probe
Structure
This is unsuitable as a chemical probe: While this
compound has been used to interrogate specific protein
targets, it is not a chemical probe and should not be used
in assays that depend on a potent and selective modulator
of the protein.
Non selective compound
Broad specificity kinase inhibitor: Dasatinib bound ~10% of kinases in a panel of 317 within 10-fold of the primary target. Karaman et al., 2008. Nat. Biotech. 26, 127-132.